D8388
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D8388
Sigma
Dimethyl pimelimidate dihydrochloride
powder
| Synonym: | Dimethyl pimelinediimidate dihydrochloride, DMP |
| CAS Number: | 58537-94-3 |
| Linear Formula: | [CH3OC(=NH)CH2CH2]2CH2 · 2HCl |
| Molecular Weight: | 259.17 |
| EC Number: | 261-320-6 |
| MDL number: | MFCD00038942 |
| PubChem Substance ID: | 24894208 |
Description
| Application | A homobifunctional cross-linking reagent. Typically reacted with primary amines in the pH range 7.0-10.0 to form amidine bonds. |
| Caution | The reagent is readily hydrolyzed at neutral pH. |
| Other Notes | Note that the amidine linkage preserves original primary amine positive charge. Incorporates a seven atom linker. |
Properties
| form | powder |
| solubility | H2O: 10 mg/mL |
| storage temp. | −20°C |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 38 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
References
| reference | Brew K, et al., Cross-linking of the components of lactose synthetase with dimethylpimelimidate. J. Biol. Chem. 250, 1434-1444, (1975) Abstract |
